• Nachiket Deshpande, River Gibbs, and Rushna Ali.
• College of Human Medicine, Michigan State University, East Lansing, Michigan, USA. Electronic address: nachiketdes@gmail.com.
• World Neurosurg. 2022 Aug 1; 164: e256-e262.

BackgroundDeep brain stimulation (DBS) is a pivotal surgical treatment for movement disorders. However, men and women have had differing opinions and referral experiences related to DBS, leading us to assess whether a gender disparity exists in the interval from a movement disorder diagnosis to DBS usage.MethodsWe performed a single-center, retrospective cohort study of 105 patients who had undergone DBS surgery for either Parkinson disease (PD) or essential tremor (ET). We compared gender differences in the median interval between the diagnosis date, DBS consultation date, and DBS surgery dates. Additionally, the patient demographics, baseline clinical characteristics, and DBS outcomes were compared between men and women.ResultsWe found no significant differences between genders in the interval from the diagnosis to DBS surgery for ET or PD. At the DBS consultation for ET, the women had had significantly greater disease severity compared with the men (P = 0.029). The baseline motor impairment without medication was similar between the men and women with PD. However, female patients with PD had experienced a significantly greater reduction compared with male patients in baseline motor impairment with medication versus without medication (P = 0.042). No minority populations were represented within the female ET and PD subgroups.ConclusionsOur study detected no gender differences in the DBS implantation timeline but alluded to a gender-specific discrepancy in DBS referral for ET. The female patients did not have a shorter duration from the ET diagnosis to DBS, despite experiencing significantly greater baseline ET severity compared with their male counterparts. Furthermore, the women with ET more often used Medicaid insurance and were without minority representation.Copyright © 2022 Elsevier Inc. All rights reserved.

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