• Abdulkadir Ünsal, Veysel Barış Turhan, Doğan Öztürk, Hakan Buluş, Gülsüm Feyza Türkeş, and Özcan Erel.
• Department of General Surgery, University of Medical Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
• Ulus Travma Acil Cer. 2022 Apr 1; 28 (4): 523528523-528.

BackgroundSurgical planning is critical for ongoing treatment and prognosis of the disease's course after an appendicitis diag-nosis. Ischemia-modified albumin (IMA) has been used as a biomarker for a variety of ischemia-related disorders in the past. The aim of this study is to determine the IMA level in patients with AA and to evaluate its predictive significance.MethodsA total of 139 participants were enrolled in the trial. After diagnosis and before surgery, the amount of plasma IMA was tested. Patients diagnosed with appendicitis in Group 1 (n=97) and volunteer surgical patients not diagnosed with appendicitis in Group 2 (n=42) were compared as the final diagnostic criterion.ResultsThe data of 139 patients with a mean age of 36.15 were evaluated statistically. IMA values were analyzed in both groups. The mean IMA of all patients was 0.74±0.16 AbsU. When the two groups were compared, it was seen that IMA was statistically higher in Group 1 than in the control group. While the area under the curve for IMA was 0.670, the sensitivity for the cutoff value of 0.715 was 68%, the specificity was 62%.ConclusionOur study shows that IMA values provide significant results in predicting acute appendicitis.

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