• Postgraduate medicine · Jun 2022

    Review

    The application of magnetic resonance imaging (MRI) for the prediction of surgical outcomes in trigeminal neuralgia.

    • Zairan Wang, Zijun Zhao, Zihan Song, Yizheng Wang, and Zongmao Zhao.
    • Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
    • Postgrad Med. 2022 Jun 1; 134 (5): 480-486.

    AbstractTrigeminal neuralgia (TN) is a severe facial pain disorder that often requires surgical treatment. Neurovascular compression (NVC) has been widely accepted as the primary cause of classical TN (cTN). Vascular compression involving the near half of the cisternal segment of trigeminal nerve was the most likely cause of patient's symptoms. And severe NVC was a strong imaging predictor of an optimal surgical outcome. Operative treatments for cTN include microvascular decompression (MVD) and various ablative procedures. However, a significant proportion of cTN patients with significant NVC fail to achieve long-term pain relief after technically successful surgery. Neuroimaging using magnetic resonance imaging (MRI) provides a noninvasive method to generate objective biomarkers of eventual response to TN surgery. This paper reviewed the progress of research on the prediction of surgical outcomes in TN with MRI.

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