• Natl Med J India · Sep 2021

    Case Reports

    Severe autoimmune-mediated thrombocytopenia in an elderly woman.

    • Mingli Wei, Huaiyu Ding, and Yanfu Wang.
    • Department of Geratology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Road, Dalian 116011, Liaoning province, China.
    • Natl Med J India. 2021 Sep 1; 34 (5): 280-281.

    AbstractThe efficacy of immunotherapies that use antibodies to block programmed cell death 1 (PD-1) has been extensively investigated for lung cancer. Along with reactivation of the patient's immune response to tumour cells, immune-related adverse effects with anti-PD1 therapy have been reported. We report an 80-year-old woman who had suffered from a primary lung adenocarcinoma pre-treated with pembrolizumab and was admitted to our hospital with serious autoimmune-mediated thrombocytopenia induced by pembrolizumab.

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