Drug Safety in Episodic Migraine Management in Adults. Part 2:

Curr Pain Headache Rep · Jul 2022

Review

Drug Safety in Episodic Migraine Management in Adults. Part 2: Preventive Treatments.

The aim of this review is to aid in decision-making when choosing safe and effective options for preventive migraine medications. ⋯ In Part 2, we have compiled clinically relevant safety considerations for commonly used migraine prophylactic treatments. Preventive treatment of episodic migraine includes nonspecific and migraine-specific drugs. While medications from several pharmacological classes-such as anticonvulsants, beta-blockers, and antidepressants-have an established efficacy in migraine prevention, they are associated with a number of side effects. The safety of migraine-specific treatments such as anti-CGRP monoclonal antibodies and gepants are also discussed. This review highlights safety concerns of commonly used migraine prophylactic agents and offers suggestions on how to mitigate those risks.

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- Abigail L Chua, Sandhya Mehla, and Yulia Y Orlova.
- Geisinger Health Systems, Neurology, 1000 E. Mountain Boulevard, Wilkes-Barre, PA, 18711, USA. achua@geisinger.edu.
- Curr Pain Headache Rep. 2022 Jul 1; 26 (7): 493-504.
Purpose Of ReviewThe aim of this review is to aid in decision-making when choosing safe and effective options for preventive migraine medications.Recent FindingsIn Part 2, we have compiled clinically relevant safety considerations for commonly used migraine prophylactic treatments. Preventive treatment of episodic migraine includes nonspecific and migraine-specific drugs. While medications from several pharmacological classes-such as anticonvulsants, beta-blockers, and antidepressants-have an established efficacy in migraine prevention, they are associated with a number of side effects. The safety of migraine-specific treatments such as anti-CGRP monoclonal antibodies and gepants are also discussed. This review highlights safety concerns of commonly used migraine prophylactic agents and offers suggestions on how to mitigate those risks.© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Drug Safety in Episodic Migraine Management in Adults. Part 2: Preventive Treatments.

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