• Am. J. Med. · Nov 2022

    Domestic physical activity and new-onset hypertension: A nationwide cohort study in China.

    • Rui Li, Qinqin Li, Shaojie Zhang, Yuanyuan Zhang, Panpan He, Zhuxian Zhang, Mengyi Liu, Chun Zhou, Ziliang Ye, Qimeng Wu, Sisi Yang, Yanjun Zhang, Huan Li, Chengzhang Liu, and Xianhui Qin.
    • Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research; Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory; Guangdong Provincial Clinical Research Center for Kidney Disease, Guangzhou, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Institute of Biomedicine, Anhui Medical University, Hefei, China.
    • Am. J. Med. 2022 Nov 1; 135 (11): 13621370.e61362-1370.e6.

    BackgroundThe relation of domestic physical activity with hypertension remains uncertain. We aimed to evaluate the prospective relation of domestic physical activity and new-onset hypertension among Chinese males and females.MethodsA total of 9254 adults who were free of hypertension at baseline were enrolled from the China Health and Nutrition Survey. Data on domestic physical activity were obtained by using self-reported questionnaires, and calculated as metabolic equivalent task (MET)-hours/week. Metabolic equivalent task-hours/week may account for both intensity and time spent on activities. The study outcome was new-onset hypertension, defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or diagnosed by physician or under antihypertensive treatment during the follow-up.ResultsA total of 2892 participants developed hypertension during 81996 person-years of follow-up. Overall, there were reversed J-shaped associations between the domestic physical activity and new-onset hypertension in both males and females (both P values for nonlinearity < .001). Consistently, when domestic physical activity was assessed as categories (<10, 10 -< 20, 20 -< 30, 30 -< 40, 40 -< 50, 50 -< 60, 60 -<70, 70 -< 80, 80 -< 90, 90 -< 100, ≥100 MET-hours/week), compared with those with domestic physical activity < 10 MET-hours/week, the lower and similar risks of new-onset hypertension were found in participants with domestic physical activity 30 -< 90 MET-hours/week in both males and females.ConclusionsModerate domestic physical activity was associated with a lower risk of new-onset hypertension among both males and females.Copyright © 2022 Elsevier Inc. All rights reserved.

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