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Meta Analysis
Does adjunctive oxytocin infusion during balloon cervical ripening improve labor induction?
- Rachel Dubay, Nicola Rentschler, Dara Jolly, Jon O Neher, and Sarah Safranek.
- Valley Family Medicine, Renton, WA.
- J Fam Pract. 2022 Mar 1; 71 (2): E18-E19.
AbstractEvidence-Based Answer: Yes. Compared to the use of a transcervical balloon alone, combined cervical ripening with a balloon catheter and oxytocin shortens the time to overall delivery by 3 hours and the time to vaginal delivery by 4 hours, without altering the rate of cesarean section (strength of recommendation [SOR]: A, network meta-analysis). The effect is more pronounced in nulliparous patients (SOR: A, meta-analysis).When combined therapy is used, 6 hours of balloon time may result in faster delivery than 12 hours (SOR: B, single randomized controlled trial [RCT]). Fixed-dose oxytocin and titrated oxytocin appear to have similar effect when combined with a cervical ripening balloon (SOR: C, underpowered RCT).
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