• Best Pract Res Clin Anaesthesiol · May 2022

    Review

    Maternal sepsis.

    • Nicoletta Filetici, Marc Van de Velde, Eva Roofthooft, and Sarah Devroe.
    • IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Via della Pineta Sacchetti 217, 00168 Rome, Italy. Electronic address: nicoletta.filetici@policlinicogemelli.it.
    • Best Pract Res Clin Anaesthesiol. 2022 May 1; 36 (1): 165-177.

    AbstractMaternal sepsis is a life-threatening condition defined as organ dysfunction resulting from infection that can arise during pregnancy, childbirth, postabortion, or in the postpartum period. Validated diagnostic criteria of maternal sepsis and septic shock may reduce the impact of this condition on maternal health worldwide, but the lack of consensus on adequate tools due to the overlap between physiological adaptations that occur during pregnancy and signs and symptoms of infection and sepsis can delay both diagnosis and treatment. In the absence of evidence-based guidelines for obstetric populations, the WHO recommends the use of the "Surviving Sepsis Campaign" sepsis protocols for maternal care adapted to the local obstetric population. Interventions within the first hour from diagnosis have been proposed in 2021 to emphasize the state of emergency of a maternal sepsis. This review will highlight the utility of standardized diagnostic criteria, the implemented approaches for the prevention and treatment of maternal infections, and the strategies for early management of critically ill parturients.Copyright © 2022 Elsevier Ltd. All rights reserved.

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