• Ir J Med Sci · Apr 2023

    Multicenter Study Observational Study

    The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke.

    • Arif Aksu, Akkan Avci, Sadiye Yolcu, Adem Kaya, Begum Seyda Avci, Mustafa Oguz Tugcan, Ozan Demir, Okan Dilek, Fatih Necip Arici, Huseyin Ali Ozturk, Hilmi Erdem Sumbul, and Ferhat Icme.
    • Department of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.
    • Ir J Med Sci. 2023 Apr 1; 192 (2): 901906901-906.

    BackgroundVarious biomarkers and clinical variables are used to determine the probability risk, diagnosis, and the prognosis of acute ischemic stroke, but effective markers are still warranted.AimWe aimed to determine the effectiveness of Hs-cTnI levels to predict the prognosis of AIS.MethodsThis study was planned as a retrospective observational study. Patients with available data and over 18 years old were included in the study. Diffusion magnetic resonance images were evaluated by a senior radiologist and the infarct size was calculated.ResultsWe included 110 (54.2%) males and 93 (45.8%) females; a total of 203 patients with a mean age of 68.9 were included in the present study. Patients were divided into two groups according to the cut-off level of Hs-troponin-I (group I: lower than 8.5 mg/dL; group 2: higher than 8.5 mg/dL). These two groups were compared for mortality and infarct volume. Infarct volume and the mortality ratio of the group 2 was significantly higher [p = 0.041, U = 4294.5, LV = 6.5 (IQR = 1.8-25.4)].ConclusionsHs-troponin I may be an effective biomarker in predicting the prognosis of patients with acute ischemic stroke. Multicenter comprehensive prospective studies are warranted to obtain stronger results.© 2022. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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