• Emerg Med Australas · Aug 2022

    Intravenous chlorpromazine for acute paediatric migraine.

    • Ruth Mc Löllgen, Franz E Babl, Mark T Mackay, Ashley Hill, and Greta M Palmer.
    • Emergency Department, The Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia.
    • Emerg Med Australas. 2022 Aug 1; 34 (4): 623-625.

    ObjectiveIn paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second-line emergency treatment.MethodsRetrospective cohort study of children diagnosed with migraine at a tertiary children's hospital ED.ResultsThere were 207 children with migraine over a 1 year period. 46% received simple oral analgesia. 25% intravenous chlorpromazine, of whom 45% received further analgesia.ConclusionsWhile intravenous chlorpromazine as second-line agent was mostly safe, it had unclear efficacy given the requirement for further treatment and hospital admissions.© 2022 Australasian College for Emergency Medicine.

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