• Ann. Intern. Med. · Jul 2022

    QUAPAS: An Adaptation of the QUADAS-2 Tool to Assess Prognostic Accuracy Studies.

    • Jenny Lee, Frits Mulder, Mariska Leeflang, Robert Wolff, Penny Whiting, and Patrick M Bossuyt.
    • Department of Epidemiology and Data Science, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands (J.L., M.L., P.M.B.).
    • Ann. Intern. Med. 2022 Jul 1; 175 (7): 1010-1018.

    AbstractWhereas diagnostic tests help detect the cause of signs and symptoms, prognostic tests assist in evaluating the probable course of the disease and future outcome. Studies to evaluate prognostic tests are longitudinal, which introduces sources of bias different from those for diagnostic accuracy studies. At present, systematic reviews of prognostic tests often use the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2) tool to assess risk of bias and applicability of included studies because no equivalent instrument exists for prognostic accuracy studies.

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