• Brian Lau, Mina Tadrous, Cherry Chu, Lorian Hardcastle, and Reed F Beall.
• Department of Community Health Sciences (Lau, Hardcastle, Beall), Cumming School of Medicine, and Faculty of Law (Hardcastle), University of Calgary, Calgary, Alta.; Women's College Hospital Institute for Health System Solutions and Virtual Care (Tadrous, Chu), Leslie Dan Faculty of Pharmacy, Toronto, Ont.
• CMAJ. 2022 Jun 13; 194 (23): E801E806E801-E806.

BackgroundIn March 2020, the Government of Canada introduced measures to reduce intensifying shortages of prescription drugs during the beginning of the COVID-19 pandemic. We sought to assess the extent to which a decline in drug shortages was observed in the months after this policy change.MethodsOur data source was the Drug Shortages Canada Database, which reports shortages by drug product, including shortage start and duration. Using a cross-sectional design, we tracked shortage rates of drug products using a 30-day moving average from Apr. 15, 2017, to Apr. 1, 2022. We used autoregressive integrated moving average modelling with a ramp function to determine the significance of trend changes after policy implementation.ResultsWe found that of the 13 329 drug products at risk for shortage, 44.7% (n = 5953) had at least 1 shortage event in the past 5 years. Average daily shortage prevalence rates rose from 901 in April 2017 to a peak of 2345 by April 2020. Significant declines (p = 0.02) ensued shortly thereafter, dropping to a rate of 1611 shortages by the end of the first year after policy implementation. However, we did not observe a significant reduction in shortage rates in the second year (p = 0.2), with rates plateauing below 1500 and then rising back above 1600 by the end of March 2022.InterpretationDrug shortages are common in Canada, including during the initial months of the COVID-19 pandemic. We observed substantial improvements after the implementation of the new measures, but gains appear to have plateaued. Continued vigilance is needed to sustain improvements.© 2022 CMA Impact Inc. or its licensors.

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