• Med. Clin. North Am. · Jul 2022

    Review

    The Role of Informed Consent in Clinical and Research Settings.

    • Essa Hariri, Mazen Al Hammoud, Erin Donovan, Kevin Shah, and Michelle M Kittleson.
    • Department of Internal Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, G10 Clinic, Cleveland OH 44195, USA.
    • Med. Clin. North Am. 2022 Jul 1; 106 (4): 663-674.

    AbstractInformed consent plays an integral role in governing the patient-physician relationship with origins traced back to ancient Greek philosophy. The main pillars of informed consent are autonomy, integrity, respect, and care. In the last century, these notions have been codified into legislation to promote healthy patient-physician relationships. Understanding the process of informed consent is critical for patients, researchers, and medical practitioners. In this article, the authors provide a brief historical narrative of informed consent, elaborate on the process of obtaining an ethically and legally valid informed consent, and present some of the future challenges in the field.Copyright © 2022 Elsevier Inc. All rights reserved.

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