• Michiko Kinoshita, Yuki Ishikawa, Ryo Sekiguchi, Miyuki Matsuda, and Katsuya Tanaka.
• Department of Anesthesiology, Tokushima University Hospital, 2-50-1 Kuramoto-cho, Tokushima-shi, Tokushima, 770-8503, Japan. michiko-kinoshita@tokushima-u.ac.jp.
• J Anesth. 2022 Oct 1; 36 (5): 633-641.

PurposeWe investigated the impact of surgical masks (SM) during oxygen therapy using oxygen masks in volunteer- and simulation-based studies.MethodsFifteen volunteers wore the Hudson RCI® or Open-Face Mask® with/without an SM. The fraction of inspired oxygen concentration (FIO2), end-tidal CO2 (EtCO2), partial pressure of inspired CO2 (PICO2), and respiratory rate (RR) were measured. The oxygen flow rate increased from 0 to 10 L/min. In the simulation-based study, FIO2 was measured using a simulator that reproduced spontaneous breathing. RR was 12 or 24 bpm, and the tidal volume (Tv) was 300, 500, or 700 mL. The effect of oxygen mask fitting conditions was also examined. The primary outcome measure was FIO2 at 6 L/min.ResultsIn the volunteer-based study, FIO2 was reduced when the SM was used with the Hudson RCI® or Open-Face Mask®. The FIO2 drop was larger with the Open-Face Mask® than with the Hudson RCI®. The RR, EtCO2, and PICO2 significantly changed with the SM, but the differences were not clinically meaningful. In the simulation-based study, the SM with the Hudson RCI® did not reduce FIO2, but the SM with the Open-Face Mask® significantly decreased FIO2 under several conditions. However, the SM with the Hudson Mask® reduced FIO2 when the fit of the mask was inadequate. With the Open-Face Mask®, lower RR and Tv resulted in larger differences in FIO2.ConclusionsThe SM decreased FIO2 during oxygen therapy with oxygen masks. The impact of SM depended on the type of the oxygen mask, mask fitting, and respiratory condition.© 2022. The Author(s) under exclusive licence to Japanese Society of Anesthesiologists.

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