• Clinics · Jan 2022

    Frequency and factors associated with hospital readmission after COVID-19 hospitalization: the importance of post-COVID diarrhea.

    • Maristela Pinheiro Freire, Maura Salaroli Oliveira, Marcello Mihailenko Chaves Magri, Bruno Melo Tavares, Igor Marinho, Ana Catharina De Seixas Santos Nastri, FilhoGeraldo BusattoGBLaboratory of Psychiatric Neuroimaging (LIM-21), Department and Institute of Psychiatry, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil., HCFMUSP COVID-19 Study Group, and Anna S Levin.
    • Working Committee for Hospital Epidemiology and Infection Control, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil. Electronic address: maristelapf@uol.com.br.
    • Clinics (Sao Paulo). 2022 Jan 1; 77: 100061100061.

    PurposeThe aim of this study was to describe the incidence and risk factors for hospital readmission and infection during the months after COVID-19 hospital admission.MethodsThis prospective study included adult patients who were hospitalized due to COVID-19 and had been discharged from April 2020 to August 2020. All patients had a medical evaluation with a structured questionnaire 6 to 11 months after hospital admission. The authors included only patients with confirmed COVID-19 by RT-PCR. Patients with pregnant/postpartum women, with a proven COVID-19 reinfection or incapable of answering the questionnaire were excluded.ResultsA total of 822 patients completed the follow-up assessment, and 68% reported at least one recurrent symptom related to COVID-19. The most frequent symptom was myalgia (42%). Thirty-two percent of patients visited an emergency room after COVID-19 hospitalization, and 80 (10%) patients required re-hospitalization. Risk factors for hospital readmission were orotracheal intubation during COVID-19 hospitalization (p = 0.003, OR = 2.14), Charlson score (p = 0.002, OR = 1.21), congestive heart failure (p = 0.005, OR = 2.34), peripheral artery disease (p = 0.06, OR = 2.06) and persistent diarrhea after COVID-19 hospitalization discharge (p = 0.02, OR = 1.91). The main cause of hospital readmission was an infection, 43 (54%). Pneumonia was the most frequent infection (29%).ConclusionsThe presence of symptoms after six months of COVID-19 diagnosis was frequent, and hospital readmission was relatively high.Copyright © 2022 HCFMUSP. Published by Elsevier España, S.L.U. All rights reserved.

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