• Medicina · Jun 2022

    Review Case Reports

    Short-Term Treatment with Empagliflozin Resulted in Dehydration and Cardiac Arrest in an Elderly Patient with Specific Complications: A Case Report and Literature Review.

    • Sopak Supakul, Yurika Nishikawa, Masanori Teramura, and Tetsuro Takase.
    • Graduate School of Medicine, Keio University, Tokyo 160-8582, Japan.
    • Medicina (Kaunas). 2022 Jun 16; 58 (6).

    AbstractEmpagliflozin is a sodium-glucose cotransporter-2 inhibitor widely used in the treatment of diabetes mellitus and heart failure. Our case study involved a 68-year-old patient who was admitted to the hospital because of a cerebral infarction. The patient was simultaneously diagnosed with diabetes mellitus and heart failure, for which empagliflozin was initiated. However, food and fluid intake were reduced due to poor appetite. In addition to the side effects of empagliflozin, the patient developed severe dehydration and cardiac arrest. Careful assessment of dehydration and preventive water intake is recommended in elderly patients and those with neurological deficits, especially when receiving empagliflozin.

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