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Editorial Comment
Sex discrimination after injury: is inequity in tranexamic acid administration just the tip of the iceberg?
- Elaine Cole, Nicola Curry, and Ross Davenport.
- Centre for Trauma Sciences, Blizard Institute, Bart's & the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- Br J Anaesth. 2022 Aug 1; 129 (2): 144-147.
AbstractThere is emerging evidence of inequalities in healthcare provision between women and men. Trauma care is no exception with a number of studies indicating lower levels of prioritisation for injured female patients. The antifibrinolytic drug tranexamic acid, reduced trauma deaths to a similar extent in females and males in the international Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH) randomised controlled trials, but in real-world practice, national registry data shows females are less likely to receive tranexamic acid than males. Inequity in the provision of tranexamic acid may extend beyond sex (and gender), and further study is required to examine the effect of age and mechanism of injury differences between men and women in the decision to treat.Copyright © 2022 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.
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