• World Neurosurg · Sep 2022

    Analysis of the therapeutic effect of multi-mode mechanical thrombectomy in the treatment of acute ischemic stroke.

    • Li-Na Zhang, Qi-Yan Chen, Min Wang, Yong Wang, Da Lei, and Sheng-Li Chen.
    • Department of Neurology, ChongQing University Three Gorges Hospital, Chongqing, China.
    • World Neurosurg. 2022 Sep 1; 165: e488e493e488-e493.

    ObjectiveWe sought to observe the effectiveness and safety of multimode mechanical thrombectomy in the treatment of acute ischemic stroke.MethodsThe data from patients with acute intracranial artery occlusion treated with multimode mechanical thrombectomy between November 2018 and December 2019 were collected, and the clinical features, imaging data, treatment, and clinical follow-up results 90 days after the operation were analyzed. Postoperative recanalization and the 90-day modified Rankin Scale score were used as clinically effective endpoints. The incidence of symptomatic intracranial hemorrhage within 72 hours and postoperative 90-day mortality were used to evaluate safety.ResultsA total of 70 patients were enrolled, including 18 cases with bridging treatment, 11 cases with stent implantation, and 10 cases with balloon dilatation. During the 90 days of follow-up after surgery, 35.7% of (25/70) patients had a good prognosis (modified Rankin Scale score of 0-2). The incidence of postoperative symptomatic intracranial hemorrhage was 11.4% (8/70), and postoperative mortality was 34.3% (24/70). The onset-to-puncture time in the good-prognosis group and the poor-prognosis group was 270 (225-345) versus 330 (270-420) minutes, respectively, and the onset-to-recanalization time in the 2 groups was 350 (295-405) versus 410 (340-470) minutes, respectively. Successful recanalization in the good-prognosis group and the poor-prognosis group was 96.0% versus 57.8%, respectively, and the incidence of symptomatic intracranial hemorrhage in the 2 groups was 0% versus 17.8%, respectively. The difference between the 2 groups was statistically significant (P < 0.05).ConclusionsMultimode mechanical thrombectomy is a safe and effective therapy for the intracranial occlusion of large vessels in patients with acute ischemic stroke.Copyright © 2022 Elsevier Inc. All rights reserved.

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