• Seongjun Bak, Hye Young Choi, Jeong-Hee Lee, Jae Beom Na, Dae Seob Choi, Jae Min Cho, Ho Cheol Choi, Mi Jung Park, Ji Eun Kim, Hwa Seon Shin, Jung Ho Won, Ju-Yeon Kim, and Jae-Myung Kim.
• Department of Radiology, College of Medicine, Gyeongsang National University and Gyeongsang National University Hospital, Jinju, Republic of Korea.
• Medicine (Baltimore). 2022 Jul 1; 101 (26): e29745e29745.

RationaleMucoepidermoid carcinoma (MEC) of the breast is a rare entity, with an estimated incidence of only 0.2% to 0.3% of all primary breast tumors. The radiological features of breast MEC have scarcely been investigated mainly because of its rarity. In this article, we present a case of breast MEC diagnosed at our hospital and review the literature, focusing on radiological findings and radiologic-pathologic correlations that could improve clinical management of this entity. To the best of our knowledge, our study is the first review of the literature that focuses on the radiological features of breast MEC.Patient ConcernsA 47-year-old premenopausal woman presented with a painless palpable mass in the right breast.DiagnosisMammography and ultrasonography revealed a mass with suspicious malignant features, which was categorized as Breast Imaging Reporting and Data System category 4c. A 14-gauge core-needle biopsy revealed an intermediate-grade MEC of the breast. The patient underwent breast magnetic resonance imaging and chest computed tomography for preoperative evaluation. Postoperative histopathological examination confirmed a diagnosis of intermediate-grade MEC. The clinical staging was T2N0M0.InterventionsThe patient underwent breast-conserving surgery, adjuvant chemotherapy, radiotherapy, and hormonal therapy.OutcomesNo evidence of recurrence has been reported over 37 months.LessonsThe imaging characteristics of breast MEC were variable, and there were no specific radiological features for diagnosis. The presence of cystic components on radiological imaging is likely to be an indicator of a low-grade tumor and better prognosis, although the number of reported cases is limited.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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