• Arjun K Reddy, Jake X Checketts, Jared T Scott, Grayson R Norris, and Brent L Norris.
• Office of Medical Student Research, Oklahoma State University Center for Health Sciences, 1111W 17th St., Tulsa, OK, USA; Department of Orthopedic Surgery, Oklahoma State University Medical Center, Tulsa, OK, USA. Electronic address: arjun.k.reddy96@gmail.com.
• Injury. 2023 May 1; 54 Suppl 3: S57S60S57-S60.

AbstractSystematic reviews, of level-I primary literature, are the gold standard for the formation of Clinical Practice Guidelines in Orthopaedic Surgery. When systematic reviews have multiple groups of data, meta-analyses can be conducted to analyse the direct comparison of the data points (pairwise meta-analysis). Over recent years, statisticians have created a new statistical model called network meta-analyses that can be applied to systematic reviews. network meta-analyses allow for comparison of different treatment outcomes that may or may not have been directly assessed through level-I primary studies. network meta-analyses are appearing more and more in Orthopaedic Surgery literature; therefore, in this article, we discuss what a Network Meta-analysis is and its application in Orthopaedics.Copyright © 2022. Published by Elsevier Ltd.

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