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- Sérgio Maltês, Carvalho GouveiaCristinaCInternal Medicine Department. Hospital de São Francisco Xavier. Centro Hospitalar Lisboa Ocidental. Lisbon. Portugal., Filipa Serrazina, and Marta Rebelo.
- Cardiology Department. Hospital de Santa Cruz. Centro Hospitalar Lisboa Ocidental. Lisbon. Portugal.
- Acta Medica Port. 2023 Mar 1; 36 (3): 206209206-209.
AbstractWunderlich syndrome is a rare and possibly life-threatening haemorrhagic syndrome presenting as spontaneous nontraumatic renal rupture with subcapsular and perinephric haemorrhage. Apixaban, a direct oral anticoagulant recommended in patients with atrial fibrillation, has previously been associated with atraumatic solid organ rupture but, to date, no case of apixaban-related Wunderlich syndrome has been reported. We report a rare case of Wunderlich syndrome associated with apixaban while addressing the difficulties face by clinicians when managing anticoagulation in bleeding patients.
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