• Internal medicine · Feb 2023

    Review Case Reports

    Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review.

    • Keitaro Omori, Hiroki Kitagawa, Rie Nagaoka, Yasuhiko Naka, Kazuma Kawamoto, Yasushi Horimasu, Toshihito Nomura, Norifumi Shigemoto, Takashi Yaguchi, Noboru Hattori, and Hiroki Ohge.
    • Department of Infectious Diseases, Hiroshima University Hospital, Japan.
    • Intern. Med. 2023 Feb 1; 62 (3): 431437431-437.

    AbstractPatients after lung transplantation are at risk for Nocardia infections. We herein report a case of lung and cerebral nocardiosis caused by Nocardia elegans, a rare species of Nocardia, in a lung transplant recipient. Antibiotic therapy, including sulfamethoxazole-trimethoprim (ST), and brain abscess drainage improved symptoms and imaging findings. A literature review of N. elegans infections showed that 12 of 14 cases (85.7%) were reported from East Asia, particularly Japan (9 cases, 64.2%). The lungs were the predominant site (12/14 cases, 85.7%), and most of the cases were susceptible to ST (9/10 cases, 90%).

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