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- Emma Macdonald-Laurs, Sebastian Corlette, Andrew Davidson, and Katherine B Howell.
- Department of Neurology, The Royal Children's Hospital, Parkville, Victoria, Australia.
- Paediatr Anaesth. 2022 Oct 1; 32 (10): 1166-1168.
AbstractWe describe a two-year-old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic-clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine has not specifically been reported as potentiating seizures in Dravet syndrome, it is well-established that sodium channel blockers can worsen seizures in this population.© 2022 The Authors. Pediatric Anesthesia published by John Wiley & Sons Ltd.
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