• Neuroimaging Clin. N. Am. · Aug 2022

    Review

    Brain Connectomics.

    • Erik H Middlebrooks and Sanjeet S Grewal.
    • Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA; Department of Neurosurgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA. Electronic address: middlebrooks.erik@mayo.edu.
    • Neuroimaging Clin. N. Am. 2022 Aug 1; 32 (3): 543-552.

    AbstractA central tenet of modern neuroscience is the conceptualization of the brain as a collection of complex networks or circuits with a shift away from traditional "localizationist" theories. Connectomics seeks to unravel these brain networks and their role in the pathophysiology of neurologic diseases. This article discusses the science of connectomics with the examples of its potential role in clinical medicine and neuromodulation in multiple disorders, such as essential tremor, Parkinson's disease, obsessive-compulsive disorder, and epilepsy.Copyright © 2022 Elsevier Inc. All rights reserved.

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