• Carolina Hincapié, Johana Ascuntar, Alba León, and Fabián Jaimes.
• Universidad de Antioquia; GRAEPIC - Clinical Epidemiology Academic Group (Grupo Académico de Epidemiología Clínica); Medellín, Colombia.
• Colomb Medica. 2021 Oct 1; 52 (4): e2044287e2044287.

BackgroundqSOFA is a score to identify patients with suspected infection and risk of complications. Its criteria are like those evaluated in prognostic scores for pneumonia (CRB-65 - CURB-65), but it is not clear which is best for predicting mortality and admission to the ICU.ObjectiveCompare three scores (CURB-65, CRB-65 and qSOFA) to determine the best tool to identify emergency department patients with pneumonia at increased risk of mortality or intensive care unit (ICU) admission.MethodsSecondary analysis of three prospective cohorts of patients hospitalized with diagnosis of pneumonia in five Colombian hospitals. Validation and comparison of the score´s accuracies were performed by means of discrimination and calibration measures.ResultsCohorts 1, 2 and 3 included 158, 745 and 207 patients, with mortality rates of 32.3%, 17.2% and 18.4%, and admission to ICU was required for 52.5%, 43.5% and 25.6%, respectively. The best AUC-ROC for mortality was for CURB-65 in cohort 3 (AUC-ROC=0.67). The calibration was adequate (p>0.05) for the three scores.ConclusionsNone of these scores proved to be an appropriate predictor for mortality and admission to the ICU. Furthermore, the CRB 65 exhibited the lowest discriminative ability.Copyright © 2021 Colombia Medica.

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