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- Olivia M Seecof, Caitlyn Kuwata, Jennifer DiBiase, and Beth Popp.
- Icahn School of Medicine at Mount Sinai, Brookdale Department of Geriatrics and Palliative Care, New York, New York, USA.
- J Palliat Med. 2022 Dec 1; 25 (12): 188818911888-1891.
AbstractAlthough buprenorphine is widely accepted as a treatment option for opioid use disorder (OUD), it is underutilized as a treatment for cancer-related pain. Owing to its decreased side effect profile, various formulations (depending on FDA indication of pain versus OUD), and ability to simultaneously address OUD and pain, buprenorphine is gaining popularity in the outpatient palliative medicine setting. Despite these compelling benefits, there are significant barriers to initiating therapy. These barriers include clinician experience, insurance authorization, pharmacy supply, and stigma. We present a complicated case to describe the practical clinical experience of an attempt at low-dose initiation of buprenorphine to treat cancer-related pain in a patient with concurrent OUD and to discuss ways to start overcoming the encountered barriers.
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