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- Mariana A Martínez-Castillo, María E Medrano-Ortiz de Zárate, Alejandra Valenzuela-Pérez, Jorge A Ruiz-Romero, Félix O Quijano-Castro, and Mauricio Salcedo.
- Oncology Hospital, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social.
- Gac Med Mex. 2022 Jan 1; 158 (3): 150-156.
AbstractPrecision medicine is a reality in some diseases; it supports the development of accurate and specific diagnostic methods, new drugs and molecules. Our research team in Mexico, made up of clinical and biomedical researchers, has been performing free RET gene mutational diagnosis for medullary thyroid cancer and multiple endocrine neoplasia (MEN) 2 and 3 for 20 years. RET pathogenic variants in the Mexican population are consistent with reported data: most common mutations are 634/NEM2 and 918/NEM3. Currently, new nanobiotechnology methods are being developed for this type of determination in order to obtain faster, simpler, more sensitive and specific results applicable in all types of laboratories.Copyright: © 2022 Permanyer.
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