• Bernadette O'Connor and Sarah Doyle.
• Department of Public Health, Health Service Executive South East, Lacken, Dublin Road, Kilkenny, R95 P231, Ireland.
• Ir J Med Sci. 2019 Feb 1; 188 (1): 193-199.

BackgroundA measles outbreak occurred in age-appropriately vaccinated children in a school in a town in the South East of Ireland in September-November 2013.AimsThe purpose of this study was to investigate the risk factors associated with catching measles during the outbreak.MethodsNinety-five children (4-5 years) in three classes, in the first year of primary school, were included in the study. Immunisation records on the South East Child Health Information System for first Measles Mumps and Rubella (MMR) vaccine for the 95 children were reviewed. Data collected included age at MMR, date of administration of MMR, MMR brand and batch number, and the General Practice at which MMR was administered. The risk factors analysed included age at vaccination, time of vaccination, class and the GP practice where MMR was administered. Statistical analysis was performed using Epi info 7 and SPSS v24.ResultsThirteen children in the cohort developed measles during the outbreak. All children in the cohort were age-appropriately vaccinated, with one dose of MMR vaccine. Analysis demonstrated statistically significant differences in the relative risk of developing measles according to the class a child was in, and the General Practice at which they were vaccinated.ConclusionsThe reason for intense measles activity in one class was not established. Although a concurrent investigation into cold chain and vaccine stock management did not identify a cause for the high relative risk of measles in children vaccinated, recommendations were made for improving cold chain and vaccine stock management in General Practices.

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