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Internal medicine journal · Jul 2022
The relationship between pancreatic cancer and type 2 diabetes: the Fremantle Diabetes Study Phase I.
- DavisTimothy M ETME0000-0003-0749-7411Division of Internal Medicine, Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia. and Wendy A Davis.
- Division of Internal Medicine, Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia.
- Intern Med J. 2022 Jul 1; 52 (7): 125812621258-1262.
AbstractPancreatic cancer incidence was double (incidence rate ratio 2.06) in community-based adults with (n = 1291) versus without (n = 5158) type 2 diabetes followed for up to 25 years in the Fremantle Diabetes Study Phase 1. Sustained higher fasting plasma glucose reflecting insulin resistance and fewer comorbidities were statistically significant risk factors in the cohort with diabetes. Past pancreatitis was an aetiologically significant determinant in the cohort as a whole.© 2022 Royal Australasian College of Physicians.
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