Sepsis-induced cardiomyopathy reviewed: The case for early

J. Cardiothorac. Vasc. Anesth. · Oct 2022

Review

Sepsis-induced cardiomyopathy reviewed: The case for early consideration of mechanical support.

Sepsis-induced cardiomyopathy (SCM) is an increasingly recognized problem encountered in critical care medicine. It generally is characterized as a decrease in left, right, or biventricular ejection fraction followed by a recovery of function over a period of days to weeks. Venoarterial extracorporeal membrane oxygenation (ECMO) has been used for the treatment of adults with various etiologies of shock, including cardiogenic and septic shock. This review summarizes current pathophysiologic mechanisms leading to SCM and provides a detection and treatment algorithm for SCM, as well as a discussion about the rationale and recent clinical data surrounding the use of ECMO and other forms of mechanical circulatory support for SCM.

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- Daniel L Plack, Olivier Royer, Etienne J Couture, and Christoph G S Nabzdyk.
- Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, United States.
- J. Cardiothorac. Vasc. Anesth. 2022 Oct 1; 36 (10): 3916-3926.
AbstractSepsis-induced cardiomyopathy (SCM) is an increasingly recognized problem encountered in critical care medicine. It generally is characterized as a decrease in left, right, or biventricular ejection fraction followed by a recovery of function over a period of days to weeks. Venoarterial extracorporeal membrane oxygenation (ECMO) has been used for the treatment of adults with various etiologies of shock, including cardiogenic and septic shock. This review summarizes current pathophysiologic mechanisms leading to SCM and provides a detection and treatment algorithm for SCM, as well as a discussion about the rationale and recent clinical data surrounding the use of ECMO and other forms of mechanical circulatory support for SCM.Copyright © 2022 Elsevier Inc. All rights reserved.

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Sepsis-induced cardiomyopathy reviewed: The case for early consideration of mechanical support.

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