• Medicina · Jul 2022

    Review

    Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview.

    • Ana Maria Alexandra Stănescu, Ana-Maria-Antoaneta Cristea, Gabriel Cristian Bejan, Mariana Vieru, Anca Angela Simionescu, and Florin-Dan Popescu.
    • Department of Family Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
    • Medicina (Kaunas). 2022 Jul 9; 58 (7).

    AbstractThe dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists should consider assessing allergic contact cell-mediated hypersensitivity in selected psoriasis patients, especially those with palmoplantar psoriasis and who are refractory to topical treatments, and in patients with psoriasis, with or without arthritis, treated with biologics that present skin lesions clinically suggestive of contact dermatitis.

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