• Internal medicine · Mar 2023

    Case Reports

    A Case of Antiphospholipid Syndrome Nephropathy related Disease Diagnosed by Assessing Phosphatidylserine-dependent Antiprothrombin Antibodies.

    • Atsuhiko Suenaga, Naoki Sawa, Yoichi Oshima, Daisuke Ikuma, Yuki Oba, Masayuki Yamanouchi, Eiko Hasegawa, Hiroki Mizuno, Akinari Sekine, Tatsuya Suwabe, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Tamiko Takemura, Yutaka Yamaguchi, Motoaki Miyazono, Tatsuya Atsumi, and Yoshifumi Ubara.
    • Department of Nephrology and Rheumatology and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
    • Intern. Med. 2023 Mar 1; 62 (5): 757761757-761.

    AbstractA 42-year-old Japanese woman was admitted for the evaluation of proteinuria. She had a history of four habitual abortions and valvular heart disease, including severe mitral regurgitation and moderate tricuspid regurgitation. A kidney biopsy showed fibrointimal thickening of interlobular arteries, fibrin thrombosis, and associated focal segmental sclerosis. Although the standard test for antiphospholipid (aPL) antibodies was negative, the patient was diagnosed with antiphospholipid syndrome (APS)-related disease by testing for phosphatidylserine dependent anti-prothrombin anticardiolipin antibody, a non-criterial aPL antibody. A kidney biopsy may lead to a diagnosis of APS in patients with negative laboratory test findings for APS.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…