• Internal medicine · Feb 2023

    Case Reports

    Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin.

    • Kenta Hayashino, Junichi Zaitsu, Kazuya Kuraoka, and Taizo Hirata.
    • Department of Hematology, Okayama City Hospital, Japan.
    • Intern. Med. 2023 Feb 15; 62 (4): 655659655-659.

    AbstractMetaplastic breast cancer (MBC) is characterized by the histological presence of a mixture of epithelial and mesenchymal-like elements. However, MBC responds poorly to chemotherapy. Due to its rarity, there is no well-defined treatment for MBC. Herein, we report the case of a 56-year-old woman who underwent a mastectomy and was diagnosed with MBC with osseous differentiation classified as pT4N0M1. After the operation, she was treated with adriamycin and cisplatin, which are standard osteosarcoma treatments, resulting in a partial response. However, to determine the proper chemotherapy treatment, knowledge of the metaplastic elements of the tumor is required.

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