• Annals of medicine · Dec 2022

    Risk factors for ophthalmologic involvement and ocular findings in patients diagnosed with fungemia in a high-complexity hospital in the city of Medellín, Colombia.

    • Marcos Restrepo Arango, Juan Camilo Cadavid Usuga, Luis Fernando Velazquez Ossa, Jorge Hernando Donado Gómez, Laura Nataly Higuita Duque, and Juan Pedro Neira Gomez.
    • Ophthalmology program, School of Health Sciences, School of Medicine, Universidad Pontificia Bolivariana, Medellín, Colombia.
    • Ann. Med. 2022 Dec 1; 54 (1): 2204-2210.

    PurposeTo describe the demographic clinical characteristics and to identify the risk factors of patients diagnosed with fungemia and secondary intraocular involvement.MethodsRetrospective cohort of 97 patients diagnosed with fungemia and with or without involvement of the posterior segment. Demographic, clinical and ophthalmological variables were identified to establish the risk of retinal seeding.ResultsAn incidence of ocular involvement of 22.68% was obtained and no clear risk factor was found for subsequent showings in patients with fungemia. A risk trend was only found in patients with diabetes with an OR: 2.85; CI 95%: (0.80-10.12) and history of HIV with an OR: 2.29 CI95%: (0.85-6.12).ConclusionsIn this first cohort carried out in Colombia according to our search, findings were obtained that agree with those of other authors worldwide, where there is no evidence of a decrease in incidence compared with older studies and the absence of risk factors for the compromise of the posterior pole in patients with fungemia.KEY MESSAGESSystematic fundus evaluation by an ophthalmologist in patients with candidaemia is a recommended practice based on low-quality evidence.The identification of real risk factors for retinal compromise in fungemia would allow us to be more selective with the population to be evaluated.Fungemia generally occurs in critically ill patients, where access and availability of ophthalmology evaluation are a resource that is not always available.

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