• Luyuan Li, Kenji Ibayashi, Anthony Piscopo, Deifelt StreeseCarolinaC1Department of Neurosurgery, University of Iowa, Iowa City, Iowa., Haiming Chen, GreenleeJeremy D WJDW1Department of Neurosurgery, University of Iowa, Iowa City, Iowa., and David M Hasan.
• 1Department of Neurosurgery, University of Iowa, Iowa City, Iowa.
• J. Neurosurg. 2023 Mar 1; 138 (3): 785792785-792.

ObjectiveEndovascular electroencephalography (evEEG) uses the cerebrovascular system to record electrical activity from adjacent neural structures. The safety, feasibility, and efficacy of using the Woven EndoBridge Aneurysm Embolization System (WEB) for evEEG has not been investigated.MethodsSeventeen participants undergoing awake WEB endovascular treatment of unruptured cerebral aneurysms were included. After WEB deployment and before detachment, its distal deployment wire was connected to an EEG receiver, and participants performed a decision-making task for 10 minutes. WEB and scalp recordings were captured.ResultsAll patients underwent successful embolization and evEEG with no complications. Event-related potentials were detected on scalp EEG in 9/17 (53%) patients. Of these 9 patients, a task-related low-gamma (30-70 Hz) response on WEB channels was captured in 8/9 (89%) cases. In these 8 patients, the WEB was deployed in 2 middle cerebral arteries, 3 anterior communicating arteries, the terminal internal carotid artery, and 2 basilar tip aneurysms. Electrocardiogram artifact on WEB channels was present in 12/17 cases.ConclusionsThe WEB implanted within cerebral aneurysms of awake patients is capable of capturing task-specific brain electrical activities. Future studies are warranted to establish the efficacy of and support for evEEG as a tool for brain recording, brain stimulation, and brain-machine interface applications.

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