• Am J Emerg Med · Sep 2022

    Case Reports

    Headache and changes in artwork as a presentation of central venous sinus thrombosis in a child with acute lymphoblastic leukemia.

    • Martin A C Manoukian, Arun R Panigrahi, and Leah Tzimenatos.
    • Department of Emergency Medicine, UC Davis, Sacramento, CA, USA. Electronic address: mamanoukian@ucdavis.edu.
    • Am J Emerg Med. 2022 Sep 1; 59: 217.e1217.e3217.e1-217.e3.

    AbstractAcute lymphocytic leukemia (ALL) is a common pediatric cancer diagnosis with excellent survival outcomes but significant morbidity, particularly during the induction phase of chemotherapy. Central venous sinus thrombosis (CVST) is a known potential complication of induction therapy; however, it occurs rarely and may be difficult to diagnose, particularly in young children who have limited verbal skills. Herein, we report a case of CVST in a child with B-cell ALL undergoing induction chemotherapy whose main symptoms were headache and a change in the appearance of his artwork noticed by his parents. This astute observation by the child's parents played a critical role in his diagnosis, allowing prompt treatment and eventual recovery.Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

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