• Curr Opin Anaesthesiol · Oct 2022

    Review

    Hyperlactatemia and other perioperative metabolic disturbances in neuroanesthesia.

    • Markus Klimek, Peter de Smalen, and Joost Janssen.
    • Department of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    • Curr Opin Anaesthesiol. 2022 Oct 1; 35 (5): 537542537-542.

    Purpose Of ReviewThe concept of 'brain-body cross-talking' has gained growing interest in the last years. The understanding of the metabolic disturbances (e.g., hypernatraemia/hyponatraemia and hyperlactatemia) in neurosurgical patients has improved during the last years.Recent FindingsThe impact of elevated lactate without acidosis in neurosurgical patients remains controversial. The pathophysiology of inappropriate secretion of antidiuretic hormone (SIADH) has become clearer, whereas the diagnosis of cerebral salt wasting should be used more carefully.SummaryThese findings will contribute to a better understanding of the pathophysiology involved and enable better prevention and therapy where possible in clinical practice.Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.

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