• Isr Med Assoc J · Aug 2022

    Detection of Hepatitis D Virus: Performance in the Community.

    • Sophia Eilat-Tsanani, Amal Zoubi, and Rawi Hazzan.
    • Department of Family Medicine, Clalit Health Services, Northern Region, Nof Hagalil, Israel.
    • Isr Med Assoc J. 2022 Aug 1; 24 (8): 529-532.

    BackgroundHepatitis D virus may cause a disease at various severities in the presence of hepatitis B virus, using hepatitis B surface antigen (HBsAg) on the external envelope in its replication process. Thus, people identified with HBsAg in blood tests should also be tested for hepatitis D virus.ObjectivesTo describe the situation of performance of blood tests for detection of hepatitis D virus in patients positive for hepatitis surface antigen during 9 years in a population with heterogeneous origins in the north region of Israel.MethodsWe conducted a retrospective study using the database of Clalit Health Services.ResultsWe found 3367 people were positive for HBsAg during the study period; 613 (18%) were tested for hepatitis D. People who tested for hepatitis D were younger (47.3 ± 15 years vs. 50.5) and showed a higher rate of visiting the gastroenterology clinic (80.6% vs. 41%). The rate of positive blood tests for hepatitis D was too small for analysis, but it still demonstrated tendency for higher rates in the Ethiopian Jewish group.ConclusionsThe recommendation for performance of blood test for hepatitis D virus was followed to a small extent. Considering the ethnic diversity of the population in Israel, activities to raise rates of performance should be considered.

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