• Keon-Joo Lee, Dong Woo Shin, Hong-Kyun Park, Beom Joon Kim, Jong-Moo Park, Kyusik Kang, Tai Hwan Park, Kyung Bok Lee, Keun-Sik Hong, Yong-Jin Cho, Dong-Eog Kim, Wi-Sun Ryu, Byung-Chul Lee, Kyung-Ho Yu, Mi-Sun Oh, Soo Joo Lee, Jae Guk Kim, Jun Lee, Jae-Kwan Cha, Dae-Hyun Kim, Joon-Tae Kim, Kang-Ho Choi, Jay Chol Choi, Eva Lesén, Jonatan Hedberg, Amarjeet Tank, Edmond G Fita, Ji Eun Song, Ji Sung Lee, Juneyoung Lee, Hee-Joon Bae, and CRCS-K Investigators.
• Department of Neurology, Korea University Guro Hospital, Seoul, Korea.
• J. Korean Med. Sci. 2022 Aug 22; 37 (33): e254.

AbstractThis study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ≤ 5) or high-risk TIA (acute lesions or ≥ 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% at 3 months and 16.7% at 1 year. Incidence rate of stroke or death in the first month was 12.5 per 100 person-months: highest in patients with large artery atherosclerosis (17.0). The risk of subsequent events shortly after a minor AIS or high-risk TIA was substantial, particularly in patients with large artery atherosclerosis.© 2022 The Korean Academy of Medical Sciences.

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