• Li Li, Jinyong Huang, Xiaoqing Chen, Wenjuan Ma, Yuan Hu, and Yinglan Li.
• Nursing School, Xinjiang Medical University, Urumqi, Xinjiang Province, China; Xinjiang Medical University, Urumqi, Xinjiang Province, China; Operating Room, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, China.
• World Neurosurg. 2022 Nov 1; 167: e778e783e778-e783.

BackgroundDeep venous thrombosis (DVT) is a common clinical vascular disease, and post-thrombotic syndrome is usually the complication of patients. This study was to explore the relationship between intraoperative hypothermia and DVT.MethodsPatients who were clinically diagnosed with intracranial tumors and underwent tumors resection from January 2019 to March 2021 were studied and divided into the DVT and non-DVT group. Prothrombin time, activated partial prothrombin time (ATPP), thrombin time, plasma fibrinogen, and venous flow velocity of both lower limbs were measured to observe DVT and the incidence of DVT. Univariate and multivariate logistic regression analyses were used to investigate the correlation between intraoperative hypothermia and DVT, and to analyze the DVT-related risk factors.ResultsA total of 462 patients were analyzed, of whom 231 patients were allocated to the DVT group and 231 were in the non-DVT group. Within the DVT group, 156 patients (33.8%) experienced intraoperative hypothermia. The risk factors that were significantly correlated with DVT were age, sex, operation time, ATPP value, and intraoperative hypothermia. The decreased ATPP value was found to be significantly associated with the increased incidence of DVT, and older ages (>45 years) were highly associated with DVT. Low body temperature before operation and intraoperative hypothermia were statistically significant as well. In addition, significant association was also displayed between the patient's operation time (>350 minutes) and DVT.ConclusionPatients who underwent intracranial tumor resection experience a high incidence of DVT, and patients with intraoperative hypothermia are at greater risk of DVT.Published by Elsevier Inc.

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