• Medicina clinica · Sep 2022

    Better prognostic ability of NEWS2, SOFA and SAPS-II in septic patients.

    • Víctor Moreno-Torres, Ana Royuela, Elena Múñez, Alfonso Ortega, Ángela Gutierrez, Patricia Mills, and Antonio Ramos-Martínez.
    • Servicio de Medicina Interna, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España. Electronic address: victor.moreno.torres.1988@gmail.com.
    • Med Clin (Barc). 2022 Sep 9; 159 (5): 224229224-229.

    Background And ObjectivesTo compare the ability of qSOFA, NEWS2, SOFA, LODS, SIRS, APACHE-II and SAPS-II scores.Material And MethodsAnalysis of in-hospital mortality of 203 patients admitted to the ICU because of sepsis. The scores were compared according to their application. Discrimination was evaluated with AUC-ROC curve and performance with the Akaike's (AIC) and Bayesian information criterion (BIC).ResultsIn-hospital mortality was 31.53%. NEWS2 showed better mortality discrimination ability and better performance considering the AIC/BIC criterion for mortality tan qSOFA (AUC-ROC=.615 and .536; P=.039). SOFA presented higher performance and AUC-ROC tan LODS (.776 vs .693; P=.01) and both showed higher discrimination ability than SIRS (AUC-ROC=.521; P<.003). Finally, SAPS-II was able to predict mortality with better performance than APACHE-II and presented higher discrimination capacity but without statistical significance compared (AUROC=.738 for SAPS-II and AUROC=.673 for APACHE-II; P=.08).ConclusionNEWS2 is a better predictor of mortality than qSOFA and its implementation for the early recognition of the septic patient or the patient with higher risk in the emergency and hospitalization wards should be addressed. In addition, given that SOFA and SAPS-II showed better performance and are simpler than LODS and APACHE-II, respectively, both should be considered the scores of choice in this setting.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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