• Zhenye Li, Songbai Gui, Peng Zhao, Jiwei Bai, Lei Cao, Sen Cheng, Chunhui Liu, Haibo Zhu, Yazhuo Zhang, and Chuzhong Li.
• Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China; Beijing Institute for Brain Disorders Brain Tumor Center, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China.
• World Neurosurg. 2022 Dec 1; 168: e28e33e28-e33.

ObjectiveThis article aims to introduce an endoscopic-exoscopic technique for the resection of epidermoid cysts.MethodsWe retrospectively analyzed the intracranial epidermoid cysts patients who received whole-course combined endoscopic and exoscopic resection between 2017 and 2020 at our institution, to explore the benefit of combined endoscopic and exoscopic resection of intracranial epidermoid cysts, and evaluated the clinical utility of the endoscopic-exoscopic technique.ResultsA total of 17 patients were enrolled in the study. Of all patients, 6 patients (35.3%) underwent total resection, 10 patients (58.8%) underwent subtotal resection, and 1 patient (5.9%) underwent partial resection. Postoperative surgical complications were seen in 3 patients (17.6%), including intracranial infection in 2 patients (11.8%), and a delayed postoperative hematoma was observed in the seventh day after operation for 1 patient (5.9%), who was treated in a conservative manner and recovered smoothly from the hemorrhage. The median follow-up time was 33.3 months (range: 14.5-54.5 months). During the follow-up period, there was no recurrence of the tumors that received total resection. Two patients developed residual tumor regrowth but did not show any symptoms, therefore no further surgery was required.ConclusionsEndoscopic-exoscopic technique is safe and efficient in the resection of intracranial epidermoid cysts with panoramic views and superior maneuverability. With further development and accumulation of practical experiences, the endoscopic-exoscopic technique can also be applied in the resection of other intracranial tumors.Copyright © 2022. Published by Elsevier Inc.

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