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- Masato Sawamura, Naoki Sawa, Daisuke Ikuma, Yuki Oba, Masayuki Yamanouchi, Akinari Sekine, Hiroki Mizuno, Eiko Hasegawa, Tatsuya Suwabe, Junichi Hoshino, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, and Yoshifumi Ubara.
- Nephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
- Intern. Med. 2023 Apr 1; 62 (7): 103710411037-1041.
AbstractSystemic lupus erythematosus was diagnosed in a patient at 43 years old. When proteinuria recurred at 57 years old, the first kidney biopsy was performed, and class IV-G (A) +V lupus nephritis was diagnosed. The prednisolone dose was increased to 40 mg/day, and cyclosporine A was introduced. After 1 year, proteinuria had decreased to 0.1 g/day. Prednisolone was discontinued three years later, and cyclosporine A was continued. Thereafter, proteinuria did not reoccur. At 67 years old, a second kidney biopsy showed complete remission of lupus nephritis. Cyclosporine A enabled permanent discontinuation of glucocorticoids in a patient with lupus nephritis.
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