• Internal medicine · Nov 2022

    Case Reports

    An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection.

    • Ryoji Goto, Haruka Kawakami, Yurino Horiuchi, Ayaka Chikada, Tsutomu Yasuda, Tetsuya Suzuki, Yusuke Miyazato, Masahiro Ishikane, Yuya Kishino, Hideki Miyazaki, Toru Igari, Harutaka Katano, Tadaki Suzuki, Shigeo Murayama, and Noritoshi Arai.
    • Department of Neurology, National Center for Global Health and Medicine, Japan.
    • Intern. Med. 2022 Nov 15; 61 (22): 343934443439-3444.

    AbstractWe herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.

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