• Br J Anaesth · Oct 2022

    Editorial

    Tranexamic acid for safer surgery: the time is now.

    • UK Royal Colleges Tranexamic Acid in Surgery Implementation Group, GrocottMichael P WMPWRoyal College of Anaesthetists, London, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton/University of Southampton, Southampton, UK., Mike Murphy, Ian Roberts, Rob Sayers, and Cheng-Hock Toh.
    • Royal College of Anaesthetists, London, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton/University of Southampton, Southampton, UK.
    • Br J Anaesth. 2022 Oct 1; 129 (4): 459461459-461.

    AbstractTranexamic acid reduces surgical bleeding. Consistent with previous research, the POISE-3 (Peri-Operative Ischemic Evaluation-3) trial found that tranexamic acid reduces major bleeding by 25% and with a low probability of any increase in thromboembolic events. Wider tranexamic acid use will improve surgical safety, avoid unnecessary blood use, reduce the risk of transfusion transmitted infections, and save healthcare funds. 'Consideration of tranexamic acid use' should be included in the safe surgery checklist. We have the evidence, and we need to act on it.Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.

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