• Ann. Intern. Med. · Sep 2022

    Review

    Deep Venous Thrombosis.

    • Lisa Duffett.
    • The Ottawa Hospital, Ottawa, Ontario, Canada.
    • Ann. Intern. Med. 2022 Sep 1; 175 (9): ITC129-ITC144.

    AbstractVenous thromboembolism (VTE) is the third most common cardiovascular disorder, affecting up to 5% of the population. VTE commonly manifests as lower-extremity deep venous thrombosis (DVT) or pulmonary embolism. Half of these events are associated with a transient risk factor and may be preventable with prophylaxis. Direct oral anticoagulants are effective and safe and carry a lower risk for bleeding than vitamin K antagonists. Many patients with VTE will have a chronic disease requiring long-term anticoagulation. Postthrombotic syndrome affects 25% to 40% of patients with DVT and significantly impacts function and quality of life.

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