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Meta Analysis
Efficacy and safety of Goel-Harms technique in upper cervical spine surgery: a systematic review and meta-analysis.
- Ivan Lvov, Andrey Grin, Aleksandr Talypov, Vladimir Smirnov, Anton Kordonskiy, Zaali Barbakadze, Rinat Abdrafiev, and Vladimir Krylov.
- Department of Neurosurgery, Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia. Electronic address: dr.speleolog@gmail.com.
- World Neurosurg. 2022 Nov 1; 167: e1169e1184e1169-e1184.
ObjectiveThe main purpose of this systematic review and meta-analysis was to estimate the incidence of implant-associated complications and fusion rates for the Goel-Harms technique (GHT) and to show potential factors affecting the complications and nonunion development.MethodsA systematic search of the PubMed database according to PRISMA guidance was performed. The main inclusion criteria comprised description of fusion rate and/or implant-associated complications rate.ResultsThis systematic review included 86 articles focused on the results of surgery in 4208 patients. The rate of screw-related complications was as follows: 1) vertebral artery (VA) injury, 2.8%; 2) screw malposition in the direction of the VA, 5.8%; and 3) C2 nerve root irritation, 6.1%. The nonunion rate was 4.2%. Transpedicular screw insertion to the C1 and C2 vertebrae were the safest regarding VA injury and correlated with lower blood loss. For C1-C2 fusion, there was no statistical difference for the different bone graft localization. C2 nerve root irritation rate did not depend on screw insertion technique. The use of a freehand technique did not correlate with a high rate of screw-related complications.ConclusionsThe Goel-Harms technique is a promising method of C1-C2 fusion, with a relatively low nonunion and VA injury rate. It can be performed safely without C-arm or navigation system assistance. Transpedicular screw insertion trajectories to the C1 and C2 vertebrae were safest regarding VA injury and blood loss volume. Further comparative studies of various C1-C2 stabilization methods with a high level of significance should be carried out to identify the optimal approach.Copyright © 2022 Elsevier Inc. All rights reserved.
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