• Medicine · Sep 2022

    Case Reports

    Middle mediastinal paraganglioma enclosing the left anterior descending artery: A case report.

    • Bing Zhang, Guofang Liu, Jian Li, and Pinghua Wan.
    • Department of Radiology, The Chenjiaqiao Hospital of Shapingba District of Chongqing, China.
    • Medicine (Baltimore). 2022 Sep 2; 101 (35): e30377.

    RationaleParagangliomas are extremely rare neuroendocrine tumors arising from ganglia. These tumors are barely found in the middle mediastinum.Patient ConcernsA 31-year-old male patient was admitted to our hospital for treatment of an middle mediastinal tumor which was found incidentally on echocardiography during a medical checkup. Contrast-enhanced chest computed tomography (CT) demonstrated a well-defined hypervascularized heterogeneous mass located in the middle mediastinum. The tumor showed strong 18F-fluorodeoxyglucose (FDG) activity on positron emission tomography-computed tomography (PET-CT).DiagnosisBefore the surgery, we presumed the mass was an angiogenic or neurogenic tumor. As a result, the histological features favored a diagnosis of paraganglioma.InterventionsThe tumor was completely removed by anterior thoracotomy, along with the proximal segment of the left anterior descending artery (LAD), and coronary artery bypass grafting (CABG) was performed immediately after the tumor excision.OutcomesThe patient had an uneventful recovery. The patient did well in the postoperative follow-up without any complications and signs of recurrence at 3 months, 1 year, 2 year and 4 year.LessonsThis report can increase the confidence in surgeries of mediastinal paragangliomas adhering tightly the adjacent structures.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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