• Ryuck Seong Kim, Changryul Claud Yi, Jae Woo Lee, Jin A Yoon, Seungbeom Lee, and Joo Hyoung Kim.
• Department of Plastic and Reconstructive Surgery, Pusan National University, School of Medicine, Busan, Korea.
• Medicine (Baltimore). 2022 Sep 16; 101 (37): e30742.

AbstractThis study aimed to compare and analyze the prognosis after lipectomy with respect to the difference in time required for indocyanine green (ICG) to reach the axilla in patients with advanced unilateral upper extremity lymphedema. The study population was divided into 2 groups, according to the time required by ICG to reach the axilla after injection, that is, <1 hour (<1 hour; n = 9) and over 1 hour (>1 hour; n = 8). The patient's arm volume was examined before surgery and up to 12 months after surgery. The volume difference between the 2 groups was compared using the excess volume ratio. Statistically significant differences were not observed before surgery (P = .847) and 1 month (P = .336), 3 months (P = .630), and 6 months after surgery (P = .124) between the excess volume ratio values of the < 1 hour and > 1 hour groups. A statistically significant difference was confirmed 12 months after surgery (P = .034). The difference in the time when ICG reached the axilla in patients with lymphedema was associated with prognosis after lipectomy. The difference in time could possibly be used as a variable to classify the progress of lymphedema in the future.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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