• Revista médica de Chile · Feb 2022

    Case Reports

    [Management of refractory septic shock with blood purification therapy using a special filter. Report of one case].

    • Gonzalo Ramírez-Guerrero, Romyna Baghetti-Hernández, Cristian Godoy-Tello, Francisco Villagrán-Cortés, Vicente Torres-Cifuentes, and Osvaldo Garay-Coloma.
    • Unidad de Cuidados Críticos, Hospital Carlos Van Buren, Valparaíso, Chile.
    • Rev Med Chil. 2022 Feb 1; 150 (2): 266-270.

    AbstractSepsis is one of the leading causes of death in critically ill patients with COVID-19 and blood purification therapies have a role to immunomodulate the excessive inflammatory response and improve clinical results. One of the devices designed for these therapies is the oXiris® filter, allowing to perform renal replacement therapy combined with selective adsorption of endotoxins and cytokines. We report a 55-year-old male with COVID who developed a septic shock secondary to a sepsis caused by Pseudomona aeruginosa, refractory to the usual management. A veno-venous continuous hemofiltration was started using the oXiris® filter for 48 hours. Subsequently, there was an improvement in clinical perfusion parameters and a reduction in inflammatory markers. The patient was discharged from the intensive care one month later.

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